Raynaud's disease



Epidemiology
Clinical features
Management


Epidemiology

  • Incidence: 100.00 cases per 100,000 person-years
  • Peak incidence: 30-40 years
  • Sex ratio: more common in females 2:1
Condition Relative
incidence
Raynaud's disease1
Thromboangiitis obliterans (Buerger's disease)0.10
Systemic sclerosis0.02
<1 1-5 6+ 16+ 30+ 40+ 50+ 60+ 70+ 80+

Clinical features

Management

Management
  • all patients with suspected secondary Raynaud's phenomenon should be referred to secondary care
  • first-line: calcium channel blockers e.g. nifedipine
  • IV prostacyclin (epoprostenol) infusions: effects may last several weeks/months